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Volume 19, Number 10—October 2013

Dispatch

Variant Human T-cell Lymphotropic Virus Type 1c and Adult T-cell Leukemia, Australia

Lloyd Einsiedel1Comments to Author , Olivier Cassar1, Peter Bardy, Daniel Kearney, and Antoine Gessain
Author affiliations: Flinders University/Northern Territory Rural Clinical School, Alice Springs, Northern Territory, Australia (L. Einsiedel); Institut Pasteur, Paris, France (O. Cassar, A. Gessain); Centre National de la Recherche Scientifique Unité Mixte de Recherche 3569, Paris (O. Cassar, A. Gessain); Royal Adelaide Hospital and Institute of Medical and Veterinary Science, Adelaide, South Australia, Australia (P. Bardy, D. Kearney)

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Figure 1

CD3 (A) and CD4 (B) cells immunostained with diaminobenzidine and horseradish peroxidase in lymph node biopsy sample from patient 2 (Aus-GM).  Original magnification ×40. C) Peripheral blood cells smear from adult T-lymphocytic leukemia patient 1 (Aus-NR). Tumor cells exhibiting multilobulated nuclei (or flower cells), which are mature activated CD4+ T-lymphocytes. D) Contrast-enhanced computed tomographic image of abdomen of patient 1, revealing para-aortic lymphadenopathy. E) Contrast-enhanced

Figure 1. . CD3 (A) and CD4 (B) cells immunostained with diaminobenzidine and horseradish peroxidase in lymph node biopsy sample from patient 2 (Aus-GM). Original magnification ×40. C) Peripheral blood cells smear from adult T-lymphocytic leukemia patient 1 (Aus-NR). Tumor cells exhibiting multilobulated nuclei (or flower cells), which are mature activated CD4+ T-lymphocytes. D) Contrast-enhanced computed tomographic image of abdomen of patient 1, revealing para-aortic lymphadenopathy. E) Contrast-enhanced computed tomographic image of patient 1, showing lytic bone lesion (L-1 veretebral body) with soft tissue involvement (arrow).

Main Article

1These authors equally contributed to this article.

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