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Volume 19, Number 12—December 2013

Dispatch

Concomitant Human Infections with 2 Cowpox Virus Strains in Related Cases, France, 2011

Corinne Ducournau, Audrey Ferrier-Rembert, Olivier Ferraris, Aurélie Joffre, Anne-Laure Favier, Olivier Flusin, Dieter Van Cauteren, Kaci Kecir, Brigitte Auburtin, Serge Védy, Maël Bessaud, and Christophe N. PeyrefitteComments to Author 
Author affiliations: French Army Biomedical Research Institut, Grenoble and Lyon, France (C. Ducournau, A. Ferrier-Rembert, O. Ferraris, A. Joffre, A.-L. Favier, O. Flusin, C.N. Peyrefitte); National Reference Center for Orthopoxviruses, Grenoble (C. Ducournau, O. Ferraris, C.N. Peyrefitte); French Institute for Public Health Surveillance, Lyon (D. Van Cauteren); Regional Hospital of Epinal, Epinal, France (K. Kecir, B. Auburtin); Legouest Military Hospital, Metz, France (S. Védy); UMR190 Aix Marseille University EHESP French School of Public Health, Marseille, France (M. Bessaud)

Main Article

Table

Phenotypic properties of cowpox virus isolates from 4 patients, France, 2011*

Patient no. Biologic samples in different cell lines
Isolate Morphologic characteristics of isolates after passage 2 in Vero cells
Vero MRC5 BHK21
1
High CPE
ND
ND
CEPAD332
High CPE on day 3, mean plaque size 600 μm ± 100 μm
2 (sister of patient 1)
High CPE
ND
ND
CEPAD336
High CPE on day 3, mean plaque size 600 μm ± 100 μm
3 (veterinarian)
High CPE
ND
ND
CEPAD333
High CPE on day 3, mean plaque size 600 μm ± 100 μm
4 (cousin of patients 1 and 2) No CPE Low CPE Low CPE CEPAD335 Low CPE on day 7, mean plaque size 300 μm ± 50 μm

*CPE, cytopathic effect; ND, not done.

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