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Volume 19, Number 12—December 2013

Research

Antiviral Susceptibility of Highly Pathogenic Avian Influenza A(H5N1) Viruses Isolated from Poultry, Vietnam, 2009–2011

Ha T. Nguyen, Tung Nguyen, Vasiliy P. Mishin, Katrina Sleeman, Amanda Balish, Joyce Jones, Adrian Creanga, Henju Marjuki, Timothy M. Uyeki, Dang H. Nguyen, Diep T. Nguyen, Hoa T. Do, Alexander I. Klimov, Charles T. Davis, and Larisa V. GubarevaComments to Author 
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (H.T. Nguyen, V.P. Mishin, K. Sleeman, A. Balish, J. Jones, H. Marjuki, T.M. Uyeki, A.I. Klimov, C.T. Davis, L.V. Gubareva); Battelle Memorial Institute, Atlanta (H.T. Nguyen, A. Creanga); National Center for Veterinary Diagnostics, Hanoi, Vietnam (T. Nguyen, D.H. Nguyen, D.T. Nguyen); Atlanta Research and Education Foundation, Atlanta (J. Jones)

Main Article

Figure 3

Replicative capacity of the oseltamivir-resistant highly pathogenic avian influenza A(H5N1) virus possessing the H275Y substitution and the wild type virus in (A) MDCK and MDCK-SIAT1 cell lines and (B) in the ferret upper respiratory tract; nasal washes were collected on days 1, 2, 3, 5, 7, and 9 post challenge. Of note, the limit of detection for virus titer was set at 1.3 x log10.

Figure 3. . Replicative capacity of the oseltamivir-resistant highly pathogenic avian influenza A(H5N1) virus possessing the H275Y substitution and the wild type virus in (A) MDCK and MDCK-SIAT1 cell lines and (B) in the ferret upper respiratory tract; nasal washes were collected on days 1, 2, 3, 5, 7, and 9 post challenge. Of note, the limit of detection for virus titer was set at 1.3 x log10.

Main Article

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