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Volume 19, Number 2—February 2013

CME ACTIVITY

Eastern Equine Encephalitis in Children, Massachusetts and New Hampshire,USA, 1970–2010

Michael A. Silverman, John Misasi, Sandra Smole, Henry A. Feldman, Adam B. Cohen, Sandro Santagata, Michael McManus, and Asim A. AhmedComments to Author 
Author affiliations: Author affiliations: Children's Hospital Boston, Boston, Massachusetts, USA (M.A. Silverman, J. Misasi, H.A. Feldman, S. Santagata, M. McManus, A.A. Ahmed); Department of Public Health, Boston (S. Smole); Massachusetts General Hospital, Boston (A.B. Cohen); Brigham and Women’s Hospital, Boston (S. Santagata)

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Figure 2

Association of length of prodrome with clinical outcome in children with eastern equine encephalitis. Clinical outcome at the time of hospital discharge was defined by using a modified Pediatric Cerebral Performance Category scale (PCPC) (27). Error bars represent standard deviation; the central lines are the mean. The Mann-Whitney rank-sum test was used to compare the prodrome lengths for patients with favorable outcomes with those for patients with unfavorable outcomes. Prodrome is defined as

Figure 2. . . . . . Association of length of prodrome with clinical outcome in children with eastern equine encephalitis. Clinical outcome at the time of hospital discharge was defined by using a modified Pediatric Cerebral Performance Category scale (PCPC) (27). Error bars represent standard deviation; the central lines are the mean. The Mann-Whitney rank-sum test was used to compare the prodrome lengths for patients with favorable outcomes with those for patients with unfavorable outcomes. Prodrome is defined as the time from initial illness symptom to first neurologic symptom. Unfavorable outcome is defined as a PCPC score of 4–6, which includes death and severe neurologic disabilities. Favorable outcome is defined as a PCPC score of 1–3, which includes complete recovery and mild to moderate neurologic disability.

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