Mycobacterial Lineages Causing Pulmonary and Extrapulmonary Tuberculosis, Ethiopia
Figure 1. . . Lineages of the Mycobacterium tuberculosis (MTB) complex, Ethiopia, 2006–2010. Genome sequence analysis of 4 strains representative of 36 related isolates identified them as members of a new phylogenetic lineage (lineage 7) of M. tuberculosis, which has a phylogenetic location intermediate between ancient lineage 1 and modern Lineages 2, 3, and 4, and a branch point before the deletion of the TbD1 region (3). Nomenclatures for lineage names and numbers are as proposed (4,6). Phylogeny shown is based on 13,199 nt positions that were variable in at least 1 of the 28 M. tuberculosis complex strains represented in the tree. Numbers near nodes indicate percentage of bootstrap replicates supporting the topology after 1,000 pseudoreplicates. MAF, M. africanum; MBO, M. bovis.