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Volume 19, Number 3—March 2013

Research

Effects of Vaccine Program against Pandemic Influenza A(H1N1) Virus, United States, 2009–2010

Rebekah H. Borse1, Sundar S. Shrestha, Anthony E. Fiore, Charisma Y. Atkins, James A. Singleton, Carolyn Furlow, and Martin I. MeltzerComments to Author 
Author affiliations: Author affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Main Article

Table 1

Data used to calculate effects of vaccination program against influenza A(H1N1)pdm09 virus by population subgroup*

Subgroup Population % Vaccinated No. doses recommended for full coverage % Assumed outcomes
Vaccine effectiveness† Clinical cases and hospitalizations Deaths
6 mo–9 y 39,429,115 1st dose/45, 2nd dose/23 2 doses, 4 wks apart 1st dose/0, 2nd dose/62 20.1 6.0
10–24 y (10–17 all, 18–24 NP) 59,684,833 27 1 62 22.3 8.0
Pregnant 18–64 y 5,578,782 43 1 62 2.2 4.0
25–64 y, HR, NP 33,949,395 27 1 62 13.5 24.0
25–64 y, HCW, non-HR, NP 17,451,921 36 1 62 5.6 9.0
25–64 y, contact <6 mo, non-HCW, non-HR, NP 8,933,718 23 1 62 2.5 6.0
25–64 y, non-contact <6 mo, non-HCW, non-HR, NP 96,235,755 16 1 62 24.0 30.0
>65 y
37,989,965
28
1
43
9.8
13.0
Total
299,253,484
27
1–2
NA
NA
NA
References (14,28,39) (9,14,28) (6) (24,36,40) (2,1921) (2,1921)

*NP, not pregnant; HR, high risk; HCW, health care worker; contact, household contacts and caregivers of children <6 months of age; NA, not applicable.
†Data are for effectiveness against clinical cases, hospitalizations, and deaths. For population subgroup 6 mo–9 y, we assumed the vaccine reached effectiveness levels 2 wk after full coverage (12).

Main Article

1Current affiliation: Merck & Co., Inc., Lansdale, Pennsylvania, USA.

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