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Volume 19, Number 5—May 2013

Dispatch

Delayed Diagnosis of Chronic Q Fever and Cardiac Valve Surgery

Linda M. KampschreurComments to Author , Elske Hoornenborg, Nicole H. M. Renders, Jan Jelrik Oosterheert, Joost F. Haverman, Peter Elsman, and Peter C. Wever
Author affiliations: University Medical Center Utrecht, Utrecht, the Netherlands (L.M. Kampschreur, J.J. Oosterheert); Jeroen Bosch Hospital, ‘s-Hertogenbosch, the Netherlands (L.M. Kampschreur, E. Hoornenborg, N,H.M. Renders, J.F. Haverman, P. Elsman, P.C. Wever)

Main Article

Table

Results of Coxiella burnetii and C-reactive protein testing for 3 patients with chronic Q fever and valvular cardiac disease requiring valve surgery, the Netherlands*

Case-patient Results for C. burnetii testing
C-reactive protein, mg/L
IFA†
PCR
Phase I IgG titer Phase II IgG titer
1
Before valve surgery† 32,768 65,536 Negative <6
After valve surgery
8,192
8,192
Positive
52
2
Before valve surgery 16,384 16,384 Positive 22
After valve surgery
16,384
16,384
Positive
26
3‡




After valve surgery 8,192 8,192 Positive 11

*IFA, immunofluorescence assay.
†Q fever serologic testing was performed retrospectively.
‡Serologic testing was not available before surgery.

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