Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

Volume 19, Number 5—May 2013

Research

Changes in Severity of Influenza A(H1N1)pdm09 Infection from Pandemic to First Postpandemic Season, Germany

Nicola Lehners1, Steffen Geis1, Christoph Eisenbach, Kai Neben, and Paul SchnitzlerComments to Author 
Author affiliations: Author affiliation: University of Heidelberg, Heidelberg, Germany

Main Article

Table 1

Demographic and clinical characteristics of influenza infected patients stratified by season, 2009–10 and 2010–11, University Hospital Heidelberg, Germany*

Characteristic No. (%) patients
p value
2009–10 2009–10
Total no. admitted patients 102 76
Male sex 56 (55) 36 (47) 0.32
Age, mean 18.2 38 <0.05
Days in hospital 7.6 13.9 <0.05
Admitted to ICU 14 (14) 35 (46) <0.05
Severely diseased 15 (15) 35 (46) <0.05
Died 5 (5) 9 (12) 0.05
Pregnant 4 (4) 5 (7) 0.50
Pneumonia 29 (28) 33 (43) <0.05
Mechanical ventilation 11 (11) 24 (32) <0.05
Underlying medical condition 52 (51) 57 (75) <0.05
Immunosuppression 22 (22) 41 (54) <0.05
Cancer 2 (2) 4 (5) 0.23
Blood malignancy 10 (10) 15 (20) 0.06
Solid organ transplant 7 (7) 14 (18) <0.05
Autoimmune 5 (5) 6 (8) 0.41
Other 2 (2) 3 (4) 0.65
Chronic lung disease 9 (9) 13 (17) 0.10
Cardiovascular disease 25 (25) 33 (43) <0.05
Renal impairment 9 (9) 20 (26) <0.05
Diabetes 6 (6) 11 (14) 0.05
Metabolic dysfunction 15 (15) 13 (17) 0.66
Neurologic impairment 15 (15) 8 (11) 0.41
CRP level on admission, mg/L† 34.7 (range <2.0–213.6) 69.2 (range <2.0–381.4) <0.05
Leukocyte count on admission, /nL† 9.9 [range 0.1–108.7) 9.1 (range 0.9–48.8)

*ICU, intensive care unit; CRP; C-reactive protein.
†Or the following day if not tested on admission.

Main Article

1These authors contributed equally to this article.

TOP