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Volume 19, Number 6—June 2013

Dispatch

BSE-associated Prion-Amyloid Cardiomyopathy in Primates

Susanne Krasemann, Giulia Mearini, Elisabeth Krämer, Katja Wagenführ, Walter Schulz-Schaeffer, Melanie Neumann, Walter Bodemer, Franz-Josef Kaup, Michael Beekes, Lucie Carrier, Adriano Aguzzi1, and Markus Glatzel1Comments to Author 
Author affiliations: University Medical Center Hamburg-Eppendorf, Hamburg, Germany (S. Krasemann, G. Mearini, E. Krämer, M. Neumann, L. Carrier, M. Glatzel); Robert Koch Institute, Berlin, Germany (K. Wagenführ, M. Beekes); University Hospital Göttingen, Göttingen, Germany (W. Schulz-Schaeffer); German Primate Center, Göttingen (W. Bodemer, F.-J. Kaup); University of Zurich, Zurich, Switzerland (A. Aguzzi)

Main Article

Table

Characteristics of 3 rhesus macaques in study of BSE-associated prion-amyloid cardiomyopathy*

Primate Age at inoculation Time to clinical disease, mo Disease duration, wk Cardiac PrPSc Signs of cardiac distress at autopsy
BSE inoculated 8 y 49 4 Neg Neg
5 y 59 18 Pos Pos
1 y 61 4 Neg Neg
Control 8 mo NA NA Neg Neg
17 y NA NA Neg Neg
19 y NA NA Neg Neg

*BSE, bovine spongiform encephalopathy; Neg, negative; Pos, positive; NA, not applicable.

Main Article

1These authors contributed equally to this article.

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