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Volume 19, Number 7—July 2013

Dispatch

Molecular Epidemiologic Source Tracking of Orally Transmitted Chagas Disease, Venezuela

Maikell Segovia, Hernán J. CarrascoComments to Author , Clara E. Martínez, Louisa A. Messenger, Anaibeth Nessi, Juan C. Londoño, Raul Espinosa, Cinda Martínez, Mijares Alfredo, Rafael Bonfante-Cabarcas, Michael D. Lewis, Belkisyolé A. de Noya, Michael A. Miles, and Martin S. Llewellyn
Author affiliations: Universidad Central de Venezuela Instituto de Medicina Tropical, Caracas, Venezuela (M. Segovia, H.J. Carrasco, C.E. Martínez, A. Nessi, B.A. de Noya); London School of Hygiene and Tropical Medicine, London, UK (L.A. Messenger, M.D. Lewis, M.A. Miles, M.S. Llewellyn); Universidad Central de Venezuela, Caracas (J.C. Londoño); Instituto Venezolano de los Seguros Sociales, Caracas (R. Espinosa); Instituto Venezolano de Investigaciones Científicas, Caracas (M. Alfredo); Ministerio del Poder Popular para la Salud, Maracay, Estado Aragua, Venezuela (C. Martínez); Universidad Centroccidental Lisandro Alvarado, Barquisimeto, Venezuela (R. Bonfante-Cabarcas)

Main Article

Figure 1

Unrooted neighbor joining tree showing genetic clustering among Trypanosoma cruzi isolates from an outbreak of oral disease in Caracas, Venezuela. Based on pairwise genetic distances (1 − proportion of shared alleles) between multilocus microsatellite profiles (23 loci) generated from 246 isolates and clones. Black circles indicate nodes with >60% bootstrap support. Branch color key is shown. Dashed boxes indicate isolates associated with the oral outbreak.

Figure 1. . Unrooted neighbor joining tree showing genetic clustering among Trypanosoma cruzi isolates from 2 outbreaks of oral disease in northern Venezuela. Based on pairwise genetic distances (1 – proportion of shared alleles) between multilocus microsatellite profiles (23 loci) generated from 246 isolates and clones. Black circles indicate nodes with >60% bootstrap support. Branch color key is shown. Dashed boxes indicate isolates associated with the outbreaks.

Main Article

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