Asian Musk Shrew as a Reservoir of Rat Hepatitis E Virus, China
Dawei Guan, Wei Li, Juan Su, Ling Fang, Naokazu Takeda, Takaji Wakita, Tian-Cheng Li, and Changwen Ke
Author affiliations: Center for Disease Control and Prevention of Guangdong Province, Guangzhou, China (D. Guan, W. Li, J. Su, L. Fang, C. Ke); Osaka University, Osaka, Japan (N. Takeda); National Institute of Infectious Diseases, Tokyo, Japan (T. Wakita, T.-C. Li)
Figure. . . Phylogenetic analysis of rat hepatitis E virus (HEV) isolated from Asian musk shrews (Suncus murinus) in Zhanjiang City, China. Nucleic acid sequence alignment was performed by using ClustalX 1.81 (www.clustal.org). The genetic distance was calculated by using the Kimura 2-parameter method. The phylogenetic tree, with 1,000 bootstrap replicates, was generated by the neighbor-joining method based on the partial sequence (281 nt) of HEV open reading frame 1 of genotype 1–4, wild boar, rabbit, ferret, bat, avian, and rat HEV isolates. The scale bar indicates nucleotide substitutions per site.
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