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Volume 19, Number 9—September 2013

Research

New Estimates of Incidence of Encephalitis in England

Julia Granerod1Comments to Author , Simon Cousens, Nicholas W.S. Davies1, Natasha S. Crowcroft1, and Sara L. Thomas
Author affiliations: Public Health England, London, UK (J. Granerod); London School of Hygiene and Tropical Medicine, London (S. Cousens, S.L. Thomas); Chelsea and Westminster Hospital, London (N.W.S. Davies); Public Health Ontario, Toronto, Ontario, Canada (N.S. Crowcroft)

Main Article

Table 3

Two-source capture–recapture estimates of encephalitis cases in England, November 1, 2006–October 31, 2007*

Coding and strata HES only PHE study only Both sources Estimated total no. cases (95% CI) % Completeness (95% CI)
HES PHE study
Encephalitis-specific code in any of the 20 diagnostic fields
Crude analysis 380 54 59 841 (692–991) 52 (43–61) 13 (10–17)
Stratified by age group
Children <18 y 78 15 20 172 (121–223) 57 (41–73) 20 (12–28)
Adults >18 y 290 39 39 658 (512–805) 50 (39–61) 12 (8–15)
Total for strata 368 54 59 830 (675–986)
Stratified by region
London 149 23 16 403 (254–552) 41 (26–56) 10 (5–14)
North West 168 29 38 364 (286–442) 57 (45–69) 18 (13–24)
South West 63 2 5 96 (49–143) 71 (38–100) 7 (1–14)
Total for strata
380
54
59
863 (689–1,038)


Encephalitis-specific code in primary field only
Crude analysis 234 60 53 612 (494–731) 47 (38–56) 18 (14–23)
Stratified by age group
Children <18 y 49 16 19 126 (87–165) 54 (38–71) 28 (17–39)
Adults >18 y 173 44 34 475 (358–593) 44 (33–55) 16 (11–21)
Total for strata 222 60 53 601 (478–725)
Stratified by region
London 86 23 14 265 (159–371) 38 (22–53) 14 (7–21)
North West 114 29 34 275 (211–339) 54 (42–66) 23 (16–30)
South West 34 2 5 55 (27–83) 71 (38–100) 13 (2–23)
Total for strata 234 54 53 595 (469–722)

*HES, Hospital Episode Statistics; PHE, Public Health England.

Main Article

1On behalf of the United Kingdom Public Health England Aetiology of Encephalitis Study Group (members listed at the end of this article).

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