Volume 2, Number 2—April 1996
Dispatch
Invasive Penicillin-Resistant Pneumococcal Infections: A Prevalence and Historical Cohort Study
Table
Demographic and clinical characteristics of patients with invasive penicillin-resistant S. pneumoniae (PRSP) and penicillin-sensitive S. pneumoniae (PSSP) infections
| PRSP; n = 29 (%) | PSSP; n = 180 (%) | Odds ratio (95% confidence interval) | |
|---|---|---|---|
| Demographic characteristics |
|||
| Age, years |
|||
| < 5 |
11 (38) |
39 (22) |
1.9 (0.4-9.1) |
| 5-64 |
8 (28) |
93 (52) |
Reference |
| > 64 |
10 (34) |
48 (27) |
1.9 (0.5-7.1) |
| Sex |
|||
| Male |
12 (41) |
104 (58) |
Reference |
| Female |
17 (59) |
76 (42) |
1.8 (0.6-5.4) |
| Racea |
|||
| White |
16 (55) |
100 (56) |
Reference |
| Nonwhite |
11 (38) |
68 (38) |
1.4 (0.5-3.9) |
| Clinical characteristics |
|||
| Site of infection |
|||
| Blood |
26 (90) |
171 (95) |
Reference |
| CSF |
3 (10) |
9 (5) |
0.8 (0.1-5.1) |
| Underlying medical condition |
14 (48) |
108 (60) |
1.0 (0.3-3.2) |
| Antibiotic useb |
14 (52) |
56 (39) |
2.5 (0.9-7.1) |
| No history of penicillin allergyc |
26 (90) |
163 (91) |
0.7 (0.1-3.4) |
| Previous hospitalizationd |
5 (19) |
33 (23) |
0.3 (0.1-1.5) |
| Day-care attendance |
|||
| Patients < 11 yearse |
5 (50) |
19 (50) |
1.1 (0.4-2.7) |
| Household member(s)f |
7 (26) |
10 (7) |
8.1 (2.2-30.7) |
| Residence in a long-term care facility |
|||
| (patients > 64 years)g |
2 (20) |
13 (27) |
0.7 (0.1-3.6) |
| Hospital-acquired infection |
1 (3) |
8 (4) |
0.4 (0.04-4.9) |
| Outcome |
|||
| Survived |
25 (86) |
156 (87) |
Reference |
| Died | 4 (14) | 24 (13) | 1.6 (0.4-6.3) |
a Missing information on 2 PRSP and 12 PSSP patients.
b Includes patients who had taken an antibiotic in the 3 months before illness; missing information on 2 PRSP and 36 PSSP patients.
c Missing information on 1 PSSP patient.
d Patients who were hospitalized in the 3 months before illness; missing information on 2 PRSP and 34 PSSP patients.
e Children < 11 years of age who attended day care in the 3 months before illness; children < 11 years of age, N = 56 (PRSP = 12, PSSP = 44); missing information on 2 PRSP and 6 PSSP patients.
f Patients with at least 1 child < 11 years of age (excluding the patient) in the household who attended day care in the 3 months before illness; missing information on 2 PRSP and 39 PSSP patients.
g Adults > 64 years of age who resided in a LTC facility in the 3 months before illness; adults > 64 years of age, N = 58 (PRSP = 10, PSSP = 48).
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