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Volume 2, Number 2—April 1996

Dispatch

Potential Risk for Dengue Hemorrhagic Fever: The Isolation of Serotype Dengue-3 in Mexico

Baltasar Briseño-García*, Héctor Gómez-Dantés, Enid Argott-Ramírez*, Ana-Laura Vázquez-Martínez*, Sergio Ibáñez-Bernal*, Guillermina Madrigal-Ayala*, Cuauhtémoc Ruíz-Matus, Ana Flisser*, Roberto Tapia-Conyer, and RaulMontesano
Author affiliations: *Instituto Nacional de Diagnóstico y Referencia Epidemiológicos, Dirección General de Epidemiología, Secretaría de Salud, México D.F., México; †Dirección General de Epidemiología, Secretaría de Salud, México D.F., México; ‡Present address: Centro de Investigación de Enfermedades Infecciosas, Instituto Nacional de Salud Pública, Secretaría de Salud, Cuernavaca, México

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Table

Number of isolates of dengue virus serotypes in Mexico*

Year DEN-1 DEN-2 DEN-3 DEN-5 Total
1982 2 5 0 0 7
1983 5 6 0 2 13
1984 89 2 0 38 129
1985 30 8 0 9 47
1986 65 0 0 24 89
1987 13 0 0 0 13
1988 28 0 0 0 28
1989 21 0 0 0 21
1990 6 0 0 0 6
1991 4 0 0 20 24
1992 1 5 0 19 25
1993 0 10 0 0 10
1994 15 9 0 0 24
1995
40
98
19
88
245
Total 319 143 19 200 681

* Serum samples from suspect cases were added to C6-36 cells grown in D-MEM with 5% fetal calf serum for 7 days at 28°C and incubated for 1 hour. Cells were washed and further incubated in D-MEM with 0.4% bovine albumin for identification of cytopathic effect.

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