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Volume 2, Number 4—October 1996

Synopsis

A Mathematical Model and CD4+ Lymphocyte Dynamics in HIV Infection

Tomáš Hraba* and Jaroslav Dolezal†
Author affiliations: *Institute of Molecular Genetics, Prague, Czech Republic; †Honeywell Technology Center, Prague, and Institute of Information Theory and Automation, Prague, Czech Republic

Main Article

Figure 2

Comparison of only linear (curve 1, v =1.0) T-helper activity decrease with non-linear (standard curve 2, v = 1.6). *CD4+ cell observed values are depicted as circles and those of CD8+ lymphocytes as squares. Both simulated and observed values are depicted as a percentage of normal CD4+ lymphocyte numbers (the normal value of CD8+ lymphocytes is thus 66.7%).

Figure 2. Comparison of only linear (curve 1, v =1.0) T-helper activity decrease with non-linear (standard curve 2, v = 1.6). *CD4+ cell observed values are depicted as circles and those of CD8+ lymphocytes as squares. Both simulated and observed values are depicted as a percentage of normal CD4+ lymphocyte numbers (the normal value of CD8+ lymphocytes is thus 66.7%).

Main Article

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