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Volume 20, Number 3—March 2014
CME ACTIVITY - Research

Use of Drug-Susceptibility Testing for Management of Drug-Resistant Tuberculosis, Thailand, 2004–2008

Eugene Lam, Sriprapa Nateniyom, Sara Whitehead, Amornrat Anuwatnonthakate, Patama Monkongdee, Apiratee Kanphukiew, Jiraphan Inyaphong, Wanlaya Sitti, Navarat Chiengsorn, Saiyud Moolphate, Suporn Kavinum, Narin Suriyon, Pranom Limsomboon, Junya Danyutapolchai, Chalinthorn Sinthuwattanawibool, and Laura Jean PodewilsComments to Author 
Author affiliations: US Centers for Disease Control and Prevention (US CDC), Atlanta, Georgia, USA (E. Lam, S. Whitehead, L.J. Podewils); Thailand Ministry of Public Health (MOPH), Nonthaburi, Thailand (S. Nateniyom); Thailand MOPH–US CDC, Nonthaburi (S. Whitehead, A. Anuwatnonthakate, P. Monkongdee, A. Kanphukiew, J. Danyutapolchai, C. Sinthuwattanawibool); Office of Disease Prevention and Control 7, Ubon-ratchathani, Thailand (J. Inyaphong, W. Sitti); Bangkok Metropolitan Health Administration, Bangkok Thailand (N. Chiengsorn); Research Institute of Tuberculosis (RIT-Japan), Tokyo, Japan (S. Moolphate); Tak Provincial Public Health Office, Tak, Thailand (S. Kavinum); Chiang Rai Provincial Public Health Office, Chiang Rai, Thailand (N. Suriyon); Phuket Provincial Public Health Office, Phuket, Thailand (P. Limsomboon)

Main Article

Table 3

Diagnostic turnaround for DST results for 130 RIF-resistant and MDR TB patients, Thailand 2004–2008*

Turnaround variable Median (IQR), d
RIF-resistant TB (n = 18) MDR TB (n = 112) Total RIF-resistant and MDR TB
Time from sputum collection to clinic receipt of results 75.0 (49.0–112.0) 100.0 (67.3–137.5) 97.5 (66.0–133.3)
Time from clinic receipt of results to review by physician† 9.0 (0.8–16.5) 7.0 (1.0–21.8) 7.0 (1.0–21.0)
Time from sputum collection to result review by physician† 83.0 (53.0–130.3) 111.0 (77.3–153.3) 109.5 (73.0–150.0)

*The 130 TB patients represented here were among 208 patients from 5 Thailand provinces participating in the Thailand Active TB Surveillance Network. Calculations were restricted to patients who had complete information for sputum collection date, date of receipt of DST at the clinic, and date of the first physician visit after availability of DST results. Three MDR TB patients were missing initial sputum collection date, 14 RIF-resistant and 41 MDR TB patients were missing date of receipt of DST results at the clinic, and 16 RIF-resistant and 47 MDR TB patients were missing date of first clinic visit following receipt of DST results. DST, drug susceptibility test; RIF, rifampin; MDR, multidrug-resistant; TB, tuberculosis; IQR, interquartile range.
†Represents first post-DST clinic visit.

Main Article

Page created: February 25, 2014
Page updated: February 25, 2014
Page reviewed: February 25, 2014
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