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Volume 20, Number 4—April 2014

Dispatch

Genetic Characterization of Clade 2.3.2.1 Avian Influenza A(H5N1) Viruses, Indonesia, 2012

Ni Luh Putu Indi DharmayantiComments to Author , Risza Hartawan, Pudjiatmoko, Hendra Wibawa, Hardiman, Amanda Balish, Ruben Donis, C. Todd Davis, and Gina Samaan
Author affiliations: Indonesian Research Center for Veterinary Science, Bogor, Indonesia (N.L.P.I. Dharmayanti, R. Hartawan, Hardiman); Ministry of Agriculture, Jakarta, Indonesia (Pudjiatmoko); Disease Investigation Center Wates, Jogjakarta, Indonesia (H. Wibawa); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (A. Balish, R. Donis, C.T. Davis); Centers for Disease Control and Prevention, Jakarta (G. Samaan)

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Table 1

Genetic characteristics of influenza A(H5N1) clade 2.3.2.1 viruses found in Indonesia, 2012*†

Strain name PB2
PB1-F2
HA‡
NA
M2
NS sequence
aa 627 aa 701 PB1-F2 truncation aa 66 aa 222 aa 224 Cleavage site aa 203 aa 27 aa 31 aa 80–84 del PDZ binding ligand
A/Hubei/1/2010 E D 90 aa N Q G PQRERRRKR↓G I I S Yes ESEV
A/Hong Kong/
6841/2010 E D 90 aa N Q G PQRERRRKR↓G I I S Yes ESEV
A/env/East Java/ LBM-LM13/2012 E D 57 aa N Q G PQRERRRKR↓G V I S Yes ESEV
A/duck/Sukoharjo/ BBVW-1428–9/2012 E D 57 aa N Q G PQRERRRKR↓G I I S Yes ESEV
A/duck/Bantul/ BBVW-1443-9/2012 E D 57 aa N Q G PQRERRRKR↓G I I S Yes ESEV
A/duck/Sleman/ BBVW-1463–10/2012 E D 57 aa N Q G PQRERRRKR↓G ND I S Yes ESEV
A/md/Tegal/
BBVW-1732-11/2012 ND ND ND ND Q G PQRERRRKR↓G ND ND ND ND ND
A/dk/Blitar/
BBVW-1731-11/2012 ND ND ND ND Q G PQRERRRKR↓G ND ND ND ND ND
A/dk/Tegal/
BBVW-1727-11/2012 ND ND ND ND Q G PQRERRRKR↓G ND ND ND ND ND
A/dk/Wonogiri/
BBVW-1730-11/2012 ND ND ND ND Q G PQRERRRKR↓G ND ND ND ND ND

*HA, hemagluttinen; NA, neuraminidase; M2, matrix 2; NS, nonstructural; ND, not determined.
†Numbering of the first and last nucleotide position of the gene that was sequenced is as follows: PB2, 1618–2192; PB1, 130–632; PA, 34–429; HA, 1–1710; NP, 268–755; NA, 55–1314; M, 55–919; NS, 25–690.
‡Glycosylation motif at 154 was absent for all strains.

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