Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

Volume 20, Number 4—April 2014

Research

Novel Betacoronavirus in Dromedaries of the Middle East, 2013

Patrick C.Y. Woo1Comments to Author , Susanna K.P. Lau1, Ulrich Wernery, Emily Y.M. Wong, Alan K.L. Tsang, Bobby Johnson, Cyril C.Y. Yip, Candy C.Y. Lau, Saritha Sivakumar, Jian-Piao Cai, Rachel Y.Y. Fan, Kwok-Hung Chan, Ringu Mareena, and Kwok-Yung Yuen
Author affiliations: The University of Hong Kong, Hong Kong, China (P.C.Y. Woo, S.K.P. Lau, E.Y.M. Wong, A.K.L. Tsang, C.C.Y. Yip, C.C.Y. Lau, J.-P. Cai, R.Y.Y. Fan, K.H. Chan, K.-Y. Yuen); Central Veterinary Research Laboratory, Dubai, United Arab Emirates (U. Wernery, B. Johnson, S. Sivakumar, R. Mareena)

Main Article

Figure 4

Phylogenetic analyses of spike protein of dromedary camel coronavirus (DcCoV) UAE-HKU23from dromedaries of the Middle East, 2013.The tree was constructed by the neighbor-joining method, using Jones-Taylor-Thornton substitution model with gamma distributed rate variation and bootstrap values calculated from 1,000 trees. Bootstrap values of <70% are not shown. A total of 1,366 aa positions in spike protein were included in the analysis. The tree was rooted to Breda virus (GenBank accession no.

Figure 4. . . . . . Phylogenetic analyses of spike protein of dromedary camel coronavirus (DcCoV) UAE-HKU23from dromedaries of the Middle East, 2013.The tree was constructed by the neighbor-joining method, using Jones-Taylor-Thornton substitution model with gamma distributed rate variation and bootstrap values calculated from 1,000 trees. Bootstrap values of <70% are not shown. A total of 1,366 aa positions in spike protein were included in the analysis. The tree was rooted to Breda virus (GenBank accession no. AY_427798).Betacoronavirus lineages A1 and A–D are indicated on the right. Boldface indicates the 3 strains of DcCoV UAE-HKU23 characterized in this study. Virus definitions and GenBank accession numbers (in parentheses) follow: RbCoV HKU14, rabbit CoV HKU14 (JN874559); HCoV-OC43, human CoV OC43 (NC_005147); CRCoV, canine respiratory CoV (JX860640); BCoV, bovine CoV (NC_003045); SACoV, sable antelope CoV (EF424621); GiCoV, giraffe CoV (EF424622); PHEV, porcine hemagglutinating encephalomyelitis virus (NC_007732); ECoV, equine CoV (NC_010327); MHV, murine hepatitis virus (NC_001846); RCoV, rat CoV (NC_012936); HCoV-HKU1, human CoV HKU1 (NC_006577); MERS-CoV, Middle East respiratory syndrome CoV (JX869059); Ty-BatCoV HKU4, tylonycteris bat CoV HKU4 (NC_009019); Pi-BatCoV HKU5, pipistrellus bat CoV HKU5 (NC_009020); SARSrCoV CFB, SARS-related Chinese ferret badger CoV (AY545919); SARSr-CiCoV, SARS-related palm civet CoV (AY304488); SARS-CoV, severe acute respiratory syndrome–associated human CoV (NC_004718); SARSr-Rh-BatCoV HKU3, SARS-related rhinolophus bat CoV HKU3 (DQ022305); Ro-BatCoV HKU9, rousettus bat CoV HKU9 (NC_009021); RhBatCoV HKU2, rhinolophus bat CoV HKU2 (EF203064); BWCoV-SW1, Beluga whale CoV SW1 (NC_010646); BdCoV HKU22, bottlenose dolphin CoV HKU22 (KF793824); TCoV, turkey CoV (NC_010800); IBV-partridge, partridge CoV (AY646283); IBV, infectious bronchitis virus (NC_001451); IBV-peafowl, peafowl CoV (AY641576); CCoV, canine CoV (GQ477367); FIPV, feline infectious peritonitis virus (AY994055); PRCV, porcine respiratory CoV (DQ811787); TGEV, transmissible gastroenteritis virus (DQ811789); MCoV, mink CoV (HM245925); Sc-BatCoV-512, scotophilus bat CoV 512 (NC_009657); PEDV, porcine epidemic diarrhea virus (NC_003436); Mi-BatCoV 1B, miniopterus bat CoV 1B (NC_010436); Mi-BatCoV 1A, miniopterus bat CoV 1A (NC_010437); Mi-BatCoV HKU8, miniopterus bat CoV HKU8 (NC_010438); Ro-BatCoV HKU10, rousettus bat CoV HKU10 (JQ989270); Hi-BatCoV HKU10, hipposideros bat CoV HKU10 (JQ989266); HCoV-NL63, human CoV NL63 (NC_005831); HCoV-229E, human CoV 229E (NC_002645); WiCoV HKU20, wigeon CoV HKU20 (JQ065048); MRCoV HKU18, magpie–robin CoV HKU18 (JQ065046); SpCoV HKU17, sparrow CoV HKU17 (JQ065045); NHCoV HKU19, night-heron CoV HKU19 (JQ065047); ThCoV HKU12, thrush CoV HKU12 (FJ376621); CMCoV HKU21, common-moorhen CoV HKU21 (JQ065049); WECoV HKU16, white-eye CoV HKU16 (JQ065044); MunCoV HKU13, munia CoV HKU13 (FJ376622); PorCoV HKU15, porcine CoV HKU15 (JQ065042); BuCoV HKU11, bulbul CoV HKU11 (FJ376619). Numbers at nodes represent bootstrap values. Scale bar indicates the estimated number of substitutions per 5 aa.

Main Article

1These authors contributed equally to this article.

TOP