Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

Volume 20, Number 4—April 2014

Research

Novel Betacoronavirus in Dromedaries of the Middle East, 2013

Patrick C.Y. Woo1Comments to Author , Susanna K.P. Lau1, Ulrich Wernery, Emily Y.M. Wong, Alan K.L. Tsang, Bobby Johnson, Cyril C.Y. Yip, Candy C.Y. Lau, Saritha Sivakumar, Jian-Piao Cai, Rachel Y.Y. Fan, Kwok-Hung Chan, Ringu Mareena, and Kwok-Yung Yuen
Author affiliations: The University of Hong Kong, Hong Kong, China (P.C.Y. Woo, S.K.P. Lau, E.Y.M. Wong, A.K.L. Tsang, C.C.Y. Yip, C.C.Y. Lau, J.-P. Cai, R.Y.Y. Fan, K.H. Chan, K.-Y. Yuen); Central Veterinary Research Laboratory, Dubai, United Arab Emirates (U. Wernery, B. Johnson, S. Sivakumar, R. Mareena)

Main Article

Figure 5

Phylogenetic analyses of the nucleocapsid protein of a novel coronavirus (CoV), dromedary camel CoV (DcCoV) UAE-HKU23, discovered in dromedaries of the Middle East, 2013.The tree was constructed by the neighbor-joining method, using Jones-Taylor-Thornton substitution model with gamma distributed rate variation and bootstrap values calculated from 1,000 trees. Bootstrap values of <70% are not shown. A total of 448 aa positions were included in the analysis. The tree was rooted to Breda virus (

Figure 5. . . . . . Phylogenetic analyses of the nucleocapsid protein of a novel coronavirus (CoV), dromedary camel CoV (DcCoV) UAE-HKU23, discovered in dromedaries of the Middle East, 2013.The tree was constructed by the neighbor-joining method, using Jones-Taylor-Thornton substitution model with gamma distributed rate variation and bootstrap values calculated from 1,000 trees. Bootstrap values of <70% are not shown. A total of 448 aa positions were included in the analysis. The tree was rooted to Breda virus (GenBank accession no. AY_427798). Betacoronavirus lineages A1 and A�?"D are indicated on the right. Boldface indicates the 3 strains of DcCoV UAE-HKU23 characterized in this study. Virus definitions and GenBank accession numbers (in parentheses) follow: TGEV, transmissible gastroenteritis virus (DQ811789); PRCV, porcine respiratory CoV (DQ811787); CCoV, canine CoV (GQ477367); FIPV, feline infectious peritonitis virus (AY994055); MCoV, mink CoV (HM245925); RhBatCoV HKU2, rhinolophus bat CoV HKU2 (EF203064); Mi-BatCoV 1A, miniopterus bat CoV 1A (NC_010437); Mi-BatCoV 1B, miniopterus bat CoV 1B (NC_010436); Mi-BatCoV HKU8, miniopterus bat CoV HKU8 (NC_010438); HCoV-229E, human CoV 229E (NC_002645); PEDV, porcine epidemic diarrhea virus (NC_003436); Sc-BatCoV-512, scotophilus bat CoV 512 (NC_009657); HCoV-NL63, human CoV NL63 (NC_005831); Hi-BatCoV HKU10, hipposideros bat CoV HKU10 (JQ989266); Ro-BatCoV HKU10, rousettus bat CoV HKU10 (JQ989270); RbCoV HKU14, rabbit CoV HKU14 (JN874559); HCoV-OC43, human CoV OC43 (NC_005147); PHEV, porcine hemagglutinating encephalomyelitis virus (NC_007732); CRCoV, canine respiratory CoV (JX860640); BCoV, bovine CoV (NC_003045); GiCoV, giraffe CoV (EF424622); SACoV, sable antelope CoV (EF424621); ECoV, equine CoV (NC_010327); HCoV-HKU1, human CoV HKU1 (NC_006577); MHV, murine hepatitis virus (NC_001846); RCoV, rat CoV (NC_012936); SARSr-CiCoV, SARS-related palm civet CoV (AY304488); SARS-CoV, severe acute respiratory syndrome�?"associated human CoV (NC_004718); SARSrCoV CFB, SARS-related Chinese ferret badger CoV (AY545919); SARSr-Rh-BatCoV HKU3, SARS-related rhinolophus bat CoV HKU3 (DQ022305); MERS-CoV, Middle East respiratory syndrome CoV (JX869059); Pi-BatCoV HKU5, pipistrellus bat CoV HKU5 (NC_009020); Ty-BatCoV HKU4, tylonycteris bat CoV HKU4 (NC_009019); Ro-BatCoV HKU9, rousettus bat CoV HKU9 (NC_009021); IBV, infectious bronchitis virus (NC_001451); IBV-partridge, partridge CoV (AY646283); TCoV, turkey CoV (NC_010800); IBV-peafowl, peafowl CoV (AY641576); BWCoV-SW1, Beluga whale CoV SW1 (NC_010646); BdCoV HKU22, bottlenose dolphin CoV HKU22 (KF793824); WiCoV HKU20, wigeon CoV HKU20 (JQ065048); CMCoV HKU21, common-moorhen CoV HKU21 (JQ065049); NHCoV HKU19, night-heron CoV HKU19 (JQ065047); BuCoV HKU11, bulbul CoV HKU11 (FJ376619); MunCoV HKU13, munia CoV HKU13 (FJ376622); MRCoV HKU18, magpie�?"robin CoV HKU18 (JQ065046); ThCoV HKU12, thrush CoV HKU12 (FJ376621); WECoV HKU16, white-eye CoV HKU16 (JQ065044); PorCoV HKU15, porcine CoV HKU15 (JQ065042); SpCoV HKU17, sparrow CoV HKU17 (JQ065045). Numbers at nodes represent bootstrap values. Scale bar indicates the estimated number of substitutions per 5 aa.

Main Article

1These authors contributed equally to this article.

TOP