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Volume 20, Number 4—April 2014

Research

Novel Betacoronavirus in Dromedaries of the Middle East, 2013

Patrick C.Y. Woo1Comments to Author , Susanna K.P. Lau1, Ulrich Wernery, Emily Y.M. Wong, Alan K.L. Tsang, Bobby Johnson, Cyril C.Y. Yip, Candy C.Y. Lau, Saritha Sivakumar, Jian-Piao Cai, Rachel Y.Y. Fan, Kwok-Hung Chan, Ringu Mareena, and Kwok-Yung Yuen
Author affiliations: The University of Hong Kong, Hong Kong, China (P.C.Y. Woo, S.K.P. Lau, E.Y.M. Wong, A.K.L. Tsang, C.C.Y. Yip, C.C.Y. Lau, J.-P. Cai, R.Y.Y. Fan, K.H. Chan, K.-Y. Yuen); Central Veterinary Research Laboratory, Dubai, United Arab Emirates (U. Wernery, B. Johnson, S. Sivakumar, R. Mareena)

Main Article

Table 3

Putative transcription regulatory sequence of betacoronavirus A1 members*

ORF Putative transcription regulatory sequence (distance, in bases, to AUG)�?
DcCoV UAE-HKU23 BCoV CRCoV SACoV GiCoV PHEV HCoV-OC43 ECoV
1ab UCUAAAC (140) UCUAAAC (140) UCUAAAC (140) UCUAAAC (140) UCUAAAC (140) UCUAAAC (140) UCUAAAC (140) UCUAAAC (140)
NS2 UCUAAAC (7) UCUAAAC (7) UCUAAAC (7) UCUAAAC (7) UCUAAAC (7) UCUAAAC (1) UCUAAAC (7) UCUAAAA (12)
HE ACUAAAC (9) ACUAAAC (9) ACUAAAC (9) ACUAAAC (9) ACUAAAC (9) ACUAAAC (9) AUUAAAC (9) UCUAAAC (9)
S UCUAAAC (0) UCUAAAC (0) UCUAAAC (0) UCUAAAC (0) UCUAAAC (0) UCUAAAC (0) UCUAAAC (0) UCUAAAC (0)
NS5 GGUGAAC (51) GGUAGAC (50) GGUAGAC (51) GGUAGAC (50) GGUAGAC (50) UUAAGCA (32) UCUAGCA (20/32) UAUACUUUAUAA (41)
E UCCAAAC (123) UCCAAAC (123) UCCAAAC (123) UCCAAAC (123) UCCAAAC (123) UCCAAAC (123) UCCAAAC (123) UCCAAAC (123)
M UCCAAAC (3) UCCAAAC (3) UCCAAAC (3) UCCAAAC (3) UCCAAAC (3) UCCAAAC (3) UCCAAAC (3) UCCAAAC (3)
N UCUAAAC (7) UCUAAAC (7) UCUAAAC (7) UCUAAAC (7) UCUAAAC (7) UCUAAAC (7) UCUAAAU (7) UCUAAAC (7)

*ORF, open reading frame; DcCoV, dromedary camel coronavirus; BCoV, bovine CoV; CRCoV, canine respiratory CoV; SACoV, sable antelopeCoV; GiCoV, giraffe CoV; PHEV, porcine hemagglutinating encephalomyelitis virus; HCoV, human CoV; ECoV, equine CoV; NS, nonstructural protein; HE, hemagglutinin esterase; S, spike protein; E, envelope protein; M, membrane protein; N, nucleocapsid protein.�?"�? Boldface indicates bases and distances to AUG that are different from those for DcCoV UAE-HKU23.

Main Article

1These authors contributed equally to this article.

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