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Volume 20, Number 4—April 2014

Dispatch

Complete Genome of Hepatitis E Virus from Laboratory Ferrets

Tian-Cheng LiComments to Author , Tingting Yang, Yasushi Ami, Yuriko Suzaki, Masayuki Shirakura, Noriko Kishida, Hideki Asanuma, Naokazu Takeda, and Wakita Takaji
Author affiliations: National Institute of Infectious Diseases, Tokyo, Japan (T.-C. Li, Y. Ami, Y, Suzaki, M. Shirakura, N. Kishida, H. Asanuma, W. Takaji); Affiliated Hospital of Qingdao University Medical College, Qingdao, China (T. Yang); Osaka University, Osaka, Japan (N. Takeda)

Main Article

Table 2

Nucleotide and deduced amino acid sequence identities between ferret HEV from the United States and other HEVs*

HEV strain (GenBank accession no.) Full-length genome, % Ferret HEV (AB890374)
Nucleotides, %
Amino acids, %
ORF1 ORF2 ORF3 ORF1 ORF2 ORF3
Genotype 1 (NC-001434) 53.6 51.4 58.9 50.3 51.4 56.9 22.2
Genotype 2 (M74506) 53.8 51.7 59.3 49.4 56.0 57.2 25.2
Genotype 3 (AF060668) 55.2 53.6 59.4 47.9 54.5 58.1 22.9
Genotype 4 (AJ272108) 53.9 51.5 59.5 49.4 53.5 57.5 28.8
Wild boar HEV (AB573435) 54.4 51.9 60.5 49.1 57.2 57.3 24.3
Wild boar HEV (AB602441) 54.0 51.9 59.1 50.9 57.4 57.0 31.5
Rabbit HEV (FJ906895) 54.8 57.0 60.5 51.2 55.2 57.7 23.3
Rat HEV (GU345042) 61.2 57.0 71.3 63.3 70.1 79.4 40.4
Rat HEV (JX120573) 62.6 58.1 72.8 64.9 74.1 80.0 43.5
Ferret HEV (998606) 82.4 81.4 84.9 85.9 91.5 94.2 73.1
Ferret HEV (998607) 82.4 81.3 85.1 85.9 91.3 94.8 73.1
Ferret HEV (AB890001) 99.6 99.7 99.5 100.0 99.7 99.8 100.0
Avian HEV (AY535004) 50.8 50.5 54.2 47.0 43.1 47.9 24.2
Bat HEV (JQ001749)
46.8
49.7
54.7
48.8
44.6
54.3
42.9
*HEV, hepatitis E virus; ORF, open reading frame.

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