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Volume 20, Number 5—May 2014

Dispatch

Influenza A(H5N2) Virus Antibodies in Humans after Contact with Infected Poultry, Taiwan, 2012

Ho-Sheng Wu, Ji-Rong Yang, Ming-Tsan Liu, Chin-Hui Yang, Ming-Chu Cheng, and Feng-Yee ChangComments to Author 
Author affiliations: Centers for Disease Control, Taipei, Taiwan (H.-S. Wu, J.-R. Yang, M.-T. Liu, C.-H. Yang, F.-Y. Chang); Taipei Medical University, Taipei (H.-S. Wu); Animal Health Research Institute, Taipei (M.-C. Cheng); National Defence Medical Center, Taipei (F.-Y. Chang)

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Table 1

HI antibody titers for influenza A(H5N2) virus in paired serum samples of 141 persons who had contact with infected poultry*

HI titers Total Second sample
Influenza vaccination history during previous 12 mo
<10 10 20 40 80 ≥160 A(H5N1) only Seasonal only Both None
First sample
<10 13 0 6 7 0 0 0 0 4 (30.8) 7 (53.8) 2 (15.4)
10 57 2 4 48 3 0 0 16 (28.1) 5 (8.8) 22 (38.6) 14 (24.5)
20 32 0 5 11 15 1* 0 3 (9.4) 17 (53.1) 3 (9.4) 9 (28.1)
40 39 0 1 10 22 4* 2* 3 (7.7) 13 (33.3) 9 (23.1) 14 (35.9)
80 0 0 0 0 0 0 0 0 0 0 0
≥160 0 0 0 0 0 0 0 0 0 0 0
Total 141 2 16 76 40 5 2 22 (15.6) 39 (27.7) 41 (29.0) 39 (27.7)

*Values are no. persons or no. (%) persons. Serum samples with hemagglutination inhibition (HI) titer >80 underwent microneutralization testing. Criteria for determining seroconversion in HI antibodies with regard to influenza A(H5N2) viruses: 1) a >4-fold increase in antibody titers in the paired serum samples; and 2) HI titer >80 for the second sample.

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