Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

Volume 20, Number 5—May 2014

Dispatch

Influenza A Subtype H3 Viruses in Feral Swine, United States, 2011–2012

Zhixin Feng, John A. Baroch, Li-Ping Long, Yifei Xu, Frederick L. Cunningham, Kerri Pedersen, Mark W. Lutman, Brandon S. Schmit, Andrew S. Bowman, Thomas J. DeLiberto, and Xiu-Feng WanComments to Author 
Author affiliations: Mississippi State University, Mississippi State, Mississippi, USA (Z. Feng, L.-P. Long, Y. Xu, X.-F. Wan); Jiangsu Academy of Agricultural Sciences, Nanjing, China (Z. Feng); Animal and Plant Health Inspection Service of the US Department of Agriculture, Fort Collins, Colorado, USA (J.A. Baroch, K. Pedersen, M.W. Lutman, B.S. Schmit, T.J. DeLiberto); Animal and Plant Health Inspection Service of the US Department of Agriculture, Mississippi State (F.L. Cunningham); The Ohio State University, Columbus, Ohio, USA (A.S. Bowman)

Main Article

Table

Cross-reactive antibody responses against H3 and influenza A(H1N1)pdm09 virus in 76 influenza-positive serum samples from feral swine, United States, 2011–2012*

Source, virus Antigenic cluster† No. seropositive (%)‡
GMT (95% CI)§
No. overall
seropositive
(%)¶
HI MN HI MN
Feral swine IAV
A/swine/Texas/A011040013/2012(H3N2) H3N2-β 36 (47.4) 36 (47.4) 163 (40–640) 259 (40–1,280) 25 (32.9)
Domestic swine IAV
A/swine/Ohio/11SW64/2009 (H3N2) H3N2-α 27 (35.5) 30 (39.5) 65 (40–160) 121 (40–1,280) 17 (22.4)
A/swine/Iowa/12627/2009(H3N2) H3N2-α 30 (39.5) 31 (40.8) 73 (40–320) 183 (40–1,280) 15 (19.7)
A/swine/Ohio/11SW347/2011(H3N2) H3N2-β 31 (40.8) 31 (40.8) 122 (40–640) 112 (40–1,280) 17 (22.4)
A/swine/Iowa/6368/2012(H3N2) H3N2-β 26 (34.2) 36 (47.4) 94 (0–640) 240 (40–1,280) 20 (26.3)
Human H3N2v IAV
A/IA/07/2011 32 (42.1) 31 (40.8) 109 (40–640) 313 (40–1,280) 21 (27.6)
Human seasonal IAV H3N2-β
A/Perth/16/2009 H3N2-β 12 (15.8) 5 (6.6) 76 (40–320] 121 (40–1,280) 1 (1.3)
A/Victoria/361/2011 H3N2-β 11 (14.5) 2 (2.6) 141 (40–640) 226 (40–1,280) 0
A/California/7/2009 H3N2-β 5 (6.6) 3 (3.9) 70 (40–640) 80 (40–320) 1 (1.3)

*Influenza detected by ELISA. GMT, geometric mean titer; HI, hemagglutination-inhibition; MN, microneutralization; IAV, influenza A virus.
†The antigenic cluster H3N2-α and H3N2-β were defined in (5).
‡Seropositive was defined as the HI or MN titer >40.
§Only serum with an HI or MN titer >40 are used to calculate the GMT.
¶Overall seroconversion was defined as both HI and MN titer >40.

Main Article

TOP