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Volume 20, Number 5—May 2014

CME ACTIVITY - Synopsis

Outbreaks of Kingella kingae Infections in Daycare Facilities

Pablo YagupskyComments to Author 
Author affiliation: Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel

Main Article

Table 2

Antibacterial drug prophylaxis administered and its effect on colonization rates and secondary invasive disease after Kingella kingae infections in daycare centers, United States, Israel, and France

Reference Initial carriage rate among healthy attendees (%) Antibacterial drug prophylaxis
Interval between cultures, d Post-prophylaxis carriage rate (%) Post-prophylaxis new cases
Rifampin
Amoxicillin
Dosage, 10 mg/kg 2×/d Duration, d Dosage, 40 mg/kg 2×/d Duration, d
(38) 9/17 (52.9) Yes 2 No NA 10–14 4/17 (23.5) 0/17
(39) 4/11 (36.4) Yes 2 Yes 4 2 0/10 0/11
(37) 0/27 Yes 2 Yes 2 NA ND 0/27
(35) 11/16 (68.8)† Yes 2 No NA 15 11/16† (68.8) 0/19
P. Yagupsky, unpub. data 4/36 (11.1) Yes 2 Yes 4 10 2/36 (5.6) 0/36
P. Yagupsky, unpub. data
5/11 (45.4)
Yes
2

Yes
4
12
0/11
0/11
Total 33/118 (28.0) NA 17/90 (18.9) 0/121

*ND, not done; NA, not applicable.
†As determined by a nucleic acid amplification assay. In all other cases carriage was established by culture on selective media.

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