TY - JOUR AU - Inpankaew, Tawin AU - Schär, Fabian AU - Dalsgaard, Anders AU - Khieu, Virak AU - Chimnoi, Wissanuwat AU - Chhoun, Chamnan AU - Sok, Daream AU - Marti, Hanspeter AU - Muth, Sinuon AU - Odermatt, Peter AU - Traub, Rebecca T1 - High Prevalence of Ancylostoma ceylanicum Hookworm Infections in Humans, Cambodia, 2012 T2 - Emerging Infectious Disease journal PY - 2014 VL - 20 IS - 6 SP - 976 SN - 1080-6059 AB - Ancylostoma ceylanicum, a hookworm of canids and felids in Asia, is becoming the second most common hookworm infecting humans. In 2012, we investigated the prevalence and infection dynamics of and risk factors for hookworm infections in humans and dogs in a rural Cambodian village. Over 57% of the population was infected with hookworms; of those, 52% harbored A. ceylanicum hookworms. The greatest intensities of A. ceylanicum eggs were in persons 21-30 years of age. Over 90% of dogs also harbored A. ceylanicum hookworms. Characterization of the cytochrome oxidase-1 gene divided isolates of A. ceylanicum hookworms into 2 groups, 1 containing isolates from humans only and the other a mix of isolates from humans and animals. We hypothesize that preventative chemotherapy in the absence of concurrent hygiene and animal health programs may be a factor leading to emergence of A. ceylanicum infections; thus, we advocate for a One Health approach to control this zoonosis. KW - hookworm KW - Ancylostoma ceylanicum KW - zoonosis KW - Cambodia KW - humans DO - 10.3201/eid2006.131770 UR - https://wwwnc.cdc.gov/eid/article/20/6/13-1770_article ER - End of Reference