TY - JOUR AU - Hariri, Susan AU - Markowitz, Lauri AU - Bennett, Nancy AU - Niccolai, Linda AU - Schafer, Sean AU - Bloch, Karen AU - Park, Ina AU - Scahill, Mary AU - Julian, Pamela AU - Abdullah, Nasreen AU - Levine, Diane AU - Whitney, Erin AU - Unger, Elizabeth AU - Steinau, Martin AU - Bauer, Heidi AU - Meek, James AU - Hadler, James AU - Sosa, Lynn AU - Powell, Suzanne AU - Johnson, Michelle AU - Group, HPV-IMPACT Working T1 - Monitoring Effect of Human Papillomavirus Vaccines in US Population, Emerging Infections Program, 2008–2012 T2 - Emerging Infectious Disease journal PY - 2015 VL - 21 IS - 9 SP - 1557 SN - 1080-6059 AB - In 2007, five Emerging Infections Program (EIP) sites were funded to determine the feasibility of establishing a population-based surveillance system for monitoring the effect of human papillomavirus (HPV) vaccine on pre-invasive cervical lesions. The project involved active population-based surveillance of cervical intraepithelial neoplasia grades 2 and 3 and adenocarcinoma in situ as well as associated HPV types in women >18 years of age residing in defined catchment areas; collecting relevant clinical information and detailed HPV vaccination histories for women 18–39 years of age; and estimating the annual rate of cervical cancer screening among the catchment area population. The first few years of the project provided key information, including data on HPV type distribution, before expected effect of vaccine introduction. The project’s success exemplifies the flexibility of EIP’s network to expand core activities to include emerging surveillance needs beyond acute infectious diseases. Project results contribute key information regarding the impact of HPV vaccination in the United States. KW - human papillomavirus KW - HPV KW - HPV vaccine KW - cervical precancer KW - cancer KW - cervical intraepithelial neoplasia KW - CIN KW - CIN2 KW - CIN3 KW - adenocarcinoma in situ KW - vaccine effect KW - vaccination KW - viruses KW - United States KW - Emerging Infections Program DO - 10.3201/eid2109.141841 UR - https://wwwnc.cdc.gov/eid/article/21/9/14-1841_article ER - End of Reference