TY - JOUR AU - Dierberg, Kerry AU - Dorjee, Kunchok AU - Salvo, Fulvio AU - Cronin, Wendy AU - Boddy, J’Belle AU - Cirillo, Daniela AU - Sadutshang, Tsetan AU - Chaisson, Richard T1 - Improved Detection of Tuberculosis and Multidrug-Resistant Tuberculosis among Tibetan Refugees, India T2 - Emerging Infectious Disease journal PY - 2016 VL - 22 IS - 3 SP - 463 SN - 1080-6059 AB - The incidence of tuberculosis (TB) among Tibetan refugees in India is 431 cases/100,000 persons, compared with 181 cases/100,000 persons overall in India in 2010. More than half of TB cases in these refugees occur among students, monks, and nuns in congregate settings. We sought to increase TB case detection rates for this population through active case finding and rapid molecular diagnostics. We screened 27,714 persons for symptoms of TB and tested 3,830 symptomatic persons by using an algorithm incorporating chest radiography, sputum smear microscopy, culture, and a rapid diagnostic test; 96 (2.5%) cases of TB were detected (prevalence 346 cases/100,000 persons). Of these cases, 5% were multidrug-resistant TB. Use of the rapid diagnostic test and active case finding enabled rapid detection of undiagnosed TB cases in congregate living settings, which would not have otherwise been identified. The burden of TB in the Tibetan exile population in India is extremely high and requires urgent attention. KW - tuberculosis and other mycobacteria KW - multidrug-resistant tuberculosis KW - bacteria KW - case detection KW - rapid molecular diagnostics KW - Xpert MTB/RIF KW - refugees KW - Tibet KW - India KW - tuberculosis KW - TB KW - incidence KW - prevalence KW - active case finding DO - 10.3201/eid2203.140732 UR - https://wwwnc.cdc.gov/eid/article/22/3/14-0732_article ER - End of Reference