TY - JOUR AU - Betsem, Edouard AU - Kaidarova, Zhanna AU - Stramer, Susan AU - Shaz, Beth AU - Sayers, Merlyn AU - LeParc, German AU - Custer, Brian AU - Busch, Michael AU - Murphy, Edward T1 - Correlation of West Nile Virus Incidence in Donated Blood with West Nile Neuroinvasive Disease Rates, United States, 2010–2012 T2 - Emerging Infectious Disease journal PY - 2017 VL - 23 IS - 2 SP - 212 SN - 1080-6059 AB - Over the past decade, West Nile virus (WNV) has spread across the United States. We aggregated blood donor data from 2010–2012 and then calculated the incidence of WNV RNA–positive donations and compared the incidence with neuroinvasive disease (NID) case data from the ArboNET surveillance system. Of 10,107,853 donations, 640 were confirmed positive. The seasonal WNV incidence rate per 100,000 persons was 33.4 (95% CI 22–45) in 2010, 25.7 (95% CI 15–34) in 2011, and 119.9 (95% CI 98–141) in 2012. NID to blood donor ratios were 1 in 164 (95% CI 152–178) in 2010, 1 in 158 (95% CI 145–174) in 2011, and 1 in 131 (95% CI 127–136) in 2012. We updated estimates of the ratio of NID to WNV infection rates, demonstrating stable disease penetrance over the study period. Blood donor WNV RNA screening is a valuable public health tool for WNV surveillance. KW - West Nile virus KW - WNV KW - blood donors KW - incidence KW - arbovirus KW - neuroinvasive disease KW - nucleic acid testing KW - viruses KW - United States KW - surveillance KW - demographic factors KW - seasonal variation KW - geographic variation KW - zoonoses KW - vector-borne infections KW - antibodies KW - Vaccine DO - 10.3201/eid2302.161058 UR - https://wwwnc.cdc.gov/eid/article/23/2/16-1058_article ER - End of Reference