Volume 3, Number 1—March 1997
Synopsis
Infectious Diseases and Immunity: Special Reference to Major Histocompatibility Complex
Neeloo Singh*
, S. Agrawal†, and A.K. Rastogi*
, S. Agrawal†, and A.K. Rastogi*Table 1
Frequency of HLA class II alleles with significant differences between leprosy patients and healthy controls
| Healthy controls |
Leprosy patients |
|||||
|---|---|---|---|---|---|---|
| HLA alleles | N=47 |
N=93 |
||||
| N | % | N | % | RRa | p | |
| DRB1*15 | 10 | 21.3 | 70 | 75.3 | 11.3 | <0.00001 |
| DRB1*1501 | 6 | 12.8 | 49 | 52.7 | 7.6 | <0.00001 |
| DRB1*1502 | 5 | 10.6 | 26 | 27.9 | 3.2 | <0.05 |
| DRB5*0101 | 6 | 12.8 | 49 | 52.7 | 7.6 | <0.00001 |
| DRB5*0102 | 5 | 10.6 | 26 | 27.9 | 3.2 | <0.05 |
| DQA1*0102 | 9 | 19.1 | 38 | 40.9 | 2.9 | <0.05 |
| DQA1*0103 | 13 | 27.6 | 48 | 51.6 | 2.8 | <0.05 |
| DQB1*0601 | 8 | 17.0 | 56 | 60.2 | 7.4 | <0.00001 |
| DRB1*0404 | 5 | 10.6 | 0 | 0.0 | 0.04 | <0.01 |
| DRB1*0701 | 13 | 29.8 | 11 | 11.8 | 0.3 | <0.05 |
| DRB1*1401 | 4 | 8.5 | 0 | 0.0 | 0.005 | <0.05 |
| DQB1*0503 | 16 | 36.2 | 14 | 16.1 | 0.3 | <0.05 |
aRR = relative risk
