Resistance, Remission, and Qualitative Differences in HIV Chemotherapy
Figure 3. Treatment simulations for four starting viral levels. The simulations have a common viral set-point of disease progression, and the treatment starting values are from Figure 1a,b. For all four simulations, the treatment parameters are c1=2.0, c2=1.0, c3=.1, the resistance mutation parameter is q=10-7, and the threshold value is V0=.5 (indicated by the horizontal line). The lowest starting viral level achieves remission (a), while the other three develop resistance.