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Volume 4, Number 2—June 1998

Synopsis

Enteroaggregative Escherichia coli

James P. Nataro*Comments to Author , Theodore Steiner†, and Richard L. Guerrant†
Author affiliations: *University of Maryland School of Medicine, Baltimore, Maryland, USA; †University of Virginia School of Medicine, Charlottesville, Virginia, USA

Main Article

Figure 3

Effects of enteroaggregative E. coli strain 042 on T84 cells in culture. Polarized T84 monolayers were washed and inoculated with 106 CFU of 042 and allowed to coincubate at 37°C for 6 hrs. Transmission electron microscopy reveals adherence of bacteria to the apical surface of the T84 cells without internalization. The apical brush border is effaced; cells are ballooning and will eventually be extruded from the monolayer. (J.P. Nataro and S. Sears, unpub. data). Bar, 1 mm.

Figure 3. Effects of enteroaggregative E. coli strain 042 on T84 cells in culture. Polarized T84 monolayers were washed and inoculated with 106 CFU of 042 and allowed to coincubate at 37°C for 6 hrs. Transmission electron microscopy reveals adherence of bacteria to the apical surface of the T84 cells without internalization. The apical brush border is effaced; cells are ballooning and will eventually be extruded from the monolayer. (J.P. Nataro and S. Sears, unpub. data). Bar, 1 mm.

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