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Volume 4, Number 2—June 1998

Dispatch

Clostridium septicum Infection and Hemolytic Uremic Syndrome

M. Barnham* and N. Weightman†
Author affiliations: *Harrogate General Hospital, Harrogate, United Kingdom; †Northallerton Friarage Hospital, North Yorkshire, United Kingdom

Main Article

Table

Hemolytic uremic syndrome–associated Clostridium septicum infection

Cytopeniasc
Country,
year (ref) Sex,a
age (yrs) E.colib in feces Cl. Septicum isolated from granulo- thrombo- Clinical features–outcome
USA,
1988 (8) M, 1 NSd Rash aspirate, PMe blood No Yes Abdominal rash, sepsis, convulsions, cerebritis, necrosis colon—died
England, 1993 (9) M, 4 O157 Blood, PM brain No Yes Convulsions, cerebritis, necrosis colon—died
USA,
1993 (10) F, 2 E. coli Blood, cerebrospinal fluid No Yes Sepsis, cerebritis, meningitis, necrosis colon—died
USA,
1995 (11) M, 2 O157 Abscess pus No Yes Brain abscess—recovered
England, 1997
(this study) M, 2 O157 Blood No Yes Septic shock—died

a M, male; F, female.
bEscherichia coli.
cAt HUS = at the time that hemolytic uremic syndrome was evident.
dNS, not stated.
ePM, postmortem.

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