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Volume 4, Number 4—December 1998

Synopsis

Chlamydia pneumoniae and Cardiovascular Disease

Lee Ann Campbell, Cho-Chou Kuo, and J. Thomas Grayston
Author affiliations: University of Washington, Seattle, Washington, USA

Main Article

Table

Studies of Chlamydia pneumoniae in atherosclerotic tissue

Source of specimens
(reference) Artery Type of specimen Atherosclerotic
tissuea
(% positive)
South Africa (7) Coronary Autopsy 20/36 (56) 20/36 (56)
PDAYb study (8) Coronary Autopsy 8/18 (44)
Univ. Washington (9) Coronary Atherectomy 20/38 (53)
Alaskan Natives (10) Coronary Autopsy 23/59 (39)
Louisville, Kentucky (11) Coronary Vascular surgery 7/12 (58)
Japan (12) Coronary Atherectomy 20/29 (69)
Salt Lake City, Utah (13) Coronary Atherectomy 71/90 (79)
India (14) Coronary Coronary artery bypass 4/40 (10)
California & Univ. Washington (15) Carotid Endarterectomy 37/61 (61)
Germany (16) Carotid Endarterectomy 7/50 (14)
Canada (17) Carotid Endarerectomy 54/76 (71)
Univ. Washington (18) Aorta Autopsy 7/21 (33)
Finland (19) Aorta Vascular surgery 12/12 (100)
Italy (20) Aorta Vascular surgery 26/51 (51)
United Kingdom (21) Aorta, femoral, iliac Vascular surgery 15/33 (45)
California (22) Popliteal femoral Vascular bypass 10/23 (43)
Finland (23) Aortic valve Autopsy 25/46 (54)
Sweden (24) Aortic Valve Surgery 19/39 (49)

aNumber positive by immunocytochemical staining and/or polymerase chain reaction over number tested.
bPDAY, pathobiological determinants of atherosclerosis in youth.

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