Figure 1. Distribution of the adjusted standardized infection intensities by Schistosoma mansoni predicted by the major gene model obtained from segregation analysis and used for linkage analysis. The frequency of allele A predisposing to high infection levels was estimated at 0.16 (70% of aa, 27% of Aa, and 3% of AA persons), and the three means (corresponding to vertical lines) were -0.43, 0.78, and 3.96 for aa, Aa, and AA persons, respectively, with a residual variance equal to 0.33.
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