Emerging Infectious Disease ISSN: 1080-6059

Genetic Epidemiology of Infectious Diseases in Humans: Design of Population- Based Studies

Laurent Abel*

and Alain J. Dessein†

Author affiliations: *Institut National de la Santé et de la Recherche Médicale Unit 436, Paris, France; and †Institut National de la Santé et de la Recherche Médicale Unit 399, Marseille, France

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Figure 2

Principle of sib-pair analysis. Two siblings can share 0, 1, or 2 parental marker alleles identical by descent (IBD) at any locus with respective probabilities 0.25, 0.5, and 0.25 under random segregation.

Figure 2. Principle of sib-pair analysis. Two siblings can share 0, 1, or 2 parental marker alleles identical by descent (IBD) at any locus with respective probabilities 0.25, 0.5, and 0.25 under random segregation.

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