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Volume 4, Number 4—December 1998

Dispatch

An Outbreak of Hantavirus Pulmonary Syndrome, Chile, 1997

Jorge Toro*, Jeanette D. Vega† ††, Ali S. Khan‡Comments to Author , James N. Mills‡, Paula Padula§, William Terry‡, Zaida Yadón§, Rosa Valderrama¶, Barbara A. Ellis‡, Carlos Pavletic*, Rodrigo Cerda†, Sherif R. Zaki‡, Shieh Wun-Ju‡, Richard Meyer‡, Mauricio Tapia#, Carlos Mansilla#, Michel Baro**, Jose A. Vergara**, Marisol Concha*, Gladys Calderon††, Delia Enria††, C.J. Peters‡, and Thomas G. Ksiazek‡
Author affiliations: *Ministry of Health, Santiago, Chile; †Pan American Health Organization, Santiago, Chile; ‡Centers for Disease Control and Prevention, Atlanta, Georgia, USA; §Instituto Nacional de Enfermedades Infecciosas ANLIS "Carlos G. Malbran," Buenos Aires, Argentina; ¶Aysen Region XI Health Service, Coyhaique, Chile; #Coyhaique Regional Hospital, Coyhaique, Aysen, Chile; **Llanchipal Health Services, Puerto Montt, Chile; ††Instituto Nacional de Enfermedades Virales Humanas, Pergamino, Argentina; and ‡‡Catholic University of Chile, Santiago, Chile.

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Figure 4

A) Low-power photomicrograph of lung showing interstitial pneumonitis and intraalveolar edema. B) Andes virus antigen–positive intraalveolar macrophages. C) Fine granular immunostaining of hantaviral antigens in endothelial cells of pulmonary microvasculature. (A, Hematoxylin and eosin; B,C, napthol-fast red with hematoxylin counterstain; original magnifications A x 50, B and C x 250.)

Figure 4. A) Low-power photomicrograph of lung showing interstitial pneumonitis and intraalveolar edema. B) Andes virus antigen–positive intraalveolar macrophages. C) Fine granular immunostaining of hantaviral antigens in endothelial cells of pulmonary microvasculature. (A, Hematoxylin and eosin; B,C, napthol-fast red with hematoxylin counterstain; original magnifications A x 50, B and C x 250.)

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