Tuberculosis in the Caribbean: Using Spacer Oligonucleotide Typing to Understand Strain Origin and Transmission
Figure 2. Nomenclature of the spoligotype database (from 1 to 69) based on published spoligotypes (n = 393) and on spoligotypes generated during this investigation (n = 218). The corresponding hybridization patterns for oligonucleotides 1 to 43 (black square, hybridizing; empty square, nonhybridizing) are shown. Type 1 is unique for the Beijing type pattern, whereas type 69 is unique for the Manila type pattern. Bold characters illustrate patterns that have so far been noticed only in Caribbean and neighboring Central American isolates (specific types). Unbolded characters illustrate patterns common to those reported elsewhere (ubiquitous types), whereas italicized characters with an asterisk illustrates patterns not yet found in the Caribbean. BCG and H37Rv spoligotypes are shown as controls.