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Volume 5, Number 5—October 1999

Dispatch

Diphtheria Antitoxin Levels in the Netherlands: a Population-Based Study

Hester E. de MelkerComments to Author , G.A.M. Berbers, N.J.D. Nagelkerke, and M.A.E. Conyn-van Spaendonck
Author affiliations: National Institute of Public Health and the Environment, Bilthoven, the Netherlands

Main Article

Table 6

Diphtheria immunity for persons in a nationwide sample who were completely vaccinated in the national immunization program and received the sixth diphtheria vaccination at 8 or 9 years of age, the Netherlands

Samplea <0.01 IU/ml 0.01-0.1 IU/ml ≥0.1 IU/ml Geometric mean titer(UI/ml)
(yrs) No. (95% CIb) (95% CI) (95% CI) (95% CI)
NRE
10-14 392 0.0 -- 17.5 (12.8-22.1) 82.5 (77.9-87.1) 0.30 (0.26-0.34)
15-19 282 0.4 (0.0-1.3) 30.1 (23.7-36.5) 69.4 (63.2-75.7) 0.17 (0.14-0.21)
20-24 155 1.2 (0.0-3.0) 29.4 (20.7-38.2) 69.4 (60.7-78.1) 0.16 (0.12-0.19)
25-29 80 1.6 (0.0-3.7) 28.3 (17.2-39.4) 70.2 (58.7-81.6) 0.14 (0.11-0.18)
30-34 52 4.3 (0.0-9.2) 54.0 (39.3-68.8) 41.7 (27.3-56.1) 0.09 (0.07-0.13)
RE
20-34 37 0.0 -- 19.0 (3.2-34.9) 81.0 (65.1-96.8) 0.29 (0.18-0.46)

aNRE, no evidence of revaccination; RE, evidence of revaccination
bCI, confidence interval.

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