The bdr Gene Families of the Lyme Disease and Relapsing Fever Spirochetes: Potential Influence on Biology, Pathogenesis, and Evolution
David M. Roberts*, Jason A Carlyon†, Michael Theisen, and Richard T. Marconi*
Author affiliations: *Medical College of Virginia at Virginia Commonwealth University, School of Medicine, Richmond, Virginia, USA; †Yale School of Medicine, Yale University, New Haven, Connecticut, USA; ‡Statens Serum Institute, Copenhagen, Denmark
Figure 4. Immunoblot analyses demonstrating the variation in Bdr protein expression in Borrelia species and isolates. Bacteria were cultivated and prepared for analysis as described in the methods. Proteins were fractionated by SDS-PAGE, immunoblotted and screened with anti-BdrF1-B.afzelii DK1 antisera. The species and isolates analyzed are indicated above each lane in panels A, B and C. The migration positions of the protein standards are indicated in each panel.
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