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Volume 6, Number 5—October 2000

Dispatch

Antimicrobial-Drug Use and Changes in Resistance in Streptococcus pneumoniae

Daniel J. DiekemaComments to Author , Angela B. Brueggemann, and Gary V. Doern
Author affiliations: University of Iowa College of Medicine, Iowa City, Iowa

Main Article

Table 1

Change in resistancea among Streptococcus pneumoniae isolates at 23 U.S. medical centers, 1994-95 and 1997-98

Medical center No. of isolates Study period Erythromycin Change (%) Penicillin
I + Rb Change
(%)
Seattle, WA 37 1994-95 5.4 35.1
50 1997-98 30.0 24.6 38.0 2.9
Denver, CO 62 1994-95 3.2 14.5
26 1997-98 7.7 4.5 15.4 0.9
Phoenix, AZ 57 1994-95 12.3 40.4
54 1997-98 35.2 22.9 40.7 0.3
Houston, TX 63 1994-95 22.2 25.4
48 1997-98 43.8 21.6 64.6 39.2
Dallas, TX 58 1994-95 6.9 22.4
36 1997-98 27.8 20.9 30.5 8.1
Rochester, MN 35 1994-95 8.6 14.2
48 1997-98 20.8 12.2 22.9 8.7
Milwaukee, WI 65 1994-95 18.5 33.8
55 1997-98 10.9 -7.6 20.0 -13.8
Evanston, IL 49 1994-95 8.2 14.3
35 1997-98 14.3 6.1 14.3 0.0
Chicago, IL 41 1994-95 17.1 34.1
41 1997-98 19.5 2.4 19.5 -14.6
Indianapolis, IN 63 1994-95 7.9 20.7
55 1997-98 18.2 10.3 25.5 4.8
St. Louis, MO 57 1994-95 8.9 24.6
55 1997-98 12.7 3.8 29.1 4.5
Detroit, MI 63 1994-95 6.3 19.0
60 1997-98 10.0 3.7 30.0 11.9
Cleveland, OH 42 1994-95 11.9 19.0
60 1997-98 20.0 8.1 23.2 4.2
Philadelphia, PA 47 1994-95 2.1 2.1
42 1997-98 11.9 9.8 21.4 19.3
Syracuse, NY 23 1994-95 8.7 8.7
50 1997-98 8.0 -0.7 20.0 11.3
Rochester, NY 58 1994-95 6.9 10.4
50 1997-98 12.0 5.1 20.0 9.6
New York, NY 64 1994-95 4.7 12.6
53 1997-98 3.8 -0.9 20.8 8.2
Hartford, CT 61 1994-95 3.3 8.2
51 1997-98 7.8 4.5 27.4 19.2
Washington, DC 60 1994-95 13.3 23.3
28 1997-98 28.6 15.3 35.7 12.4
Chapel Hill, NC 60 1994-95 10.0 31.7
49 1997-98 38.8 28.8 57.1 25.4
Decatur, GA 61 1994-95 23.0 36.1
52 1997-98 26.9 3.9 44.2 8.1
Mobile, AL 68 1994-95 16.2 20.6
58 1997-98 37.9 21.7 41.3 20.7
Miami, FL 17 1994-95 5.9 52.9
27 1997-98 29.6 23.7 51.8 -1.1
TOTAL 1,211 1994-95 10.2 22.2
1,083 1997-98 20.6 10.4 31.1 8.9

aIncludes both intermediate- and high-level resistance to penicillin and erythromycin.
bI + R = both intermediate and fully resistant.

Main Article

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