Figure 5. Three-dimensional graph of estimated mean community level of infection over time (20 years) as a function of the proportion of infections treated each year (20% to 100%). Results are obtained from the model described in the Appendix. Resurgence of infection (due to emergence of resistance) was predicted to occur soonest (≈7 years) when yearly treatment coverage was greatest (100%). Under the conditions of our study (25% to 75% coverage), detectable increases in community level of infection (due to resistance) were estimated to take a minimum of 10 to 15 years.
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