Emerging Infectious Disease ISSN: 1080-6059

Evidence Against Rapid Emergence of Praziquantel Resistance in Schistosoma haematobium, Kenya

Charles H. King*, Eric M. Muchiri†, and John H. Ouma†

Author affiliations: *Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Cleveland, Ohio, USA; †Ministry of Health, Nairobi, Kenya

Main Article

Figure 5

Three-dimensional graph of estimated mean community level of infection over time (20 years) as a function of the proportion of infections treated each year (20% to 100%). Results are obtained from the model described in the Appendix. Resurgence of infection (due to emergence of resistance) was predicted to occur soonest (≈7 years) when yearly treatment coverage was greatest (100%). Under the conditions of our study (25% to 75% coverage), detectable increases in community level of infection (due

Figure 5. Three-dimensional graph of estimated mean community level of infection over time (20 years) as a function of the proportion of infections treated each year (20% to 100%). Results are obtained from the model described in the Appendix. Resurgence of infection (due to emergence of resistance) was predicted to occur soonest (≈7 years) when yearly treatment coverage was greatest (100%). Under the conditions of our study (25% to 75% coverage), detectable increases in community level of infection (due to resistance) were estimated to take a minimum of 10 to 15 years.

Main Article

Top of Page

The opinions expressed by authors contributing to this journal do not necessarily reflect the opinions of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.