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Volume 6, Number 6—December 2000

Research

Predominance of HIV-1 Subtype A and D Infections in Uganda

Dale J. Hu*Comments to Author , James Baggs†, Robert G. Downing*†, Danuta Pieniazek*, Jonathan Dorn*, Carol Fridlund*, Benon Biryahwaho‡, Sylvester D.K. Sempala‡, Mark A. Rayfield*, Timothy J. Dondero*, and Renu B. Lal*
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †State of Washington, Department of Labor and Industries, Olympia, Washington; ‡Uganda Virus Research Institute/Centers for Disease Control and Prevention Research Collaboration, Uganda Virus Research Institute, Entebbe, Uganda

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Table 2

Mean (and range) percentage of pairwise nucleotide divergence stratified by time period, subtype, and clinic (district)

% Mean (range)
Subtype by clinic (district) 1994/95 1997 Overall
Subtype Aa
UVRIb (Mpigi) 5.0 (3.6- 9.5) 7.7 (3.9-12.6) 6.4 (3.6-12.6)
Mulago (Kampala) 7.3 (3.9-10.4) 8.3 (4.2-14.0) 7.8 (3.9-14.0)
Nsambya (Kampala) 7.3 (3.9-11.7) 10.8(3.9-22.3) 9.1 (3.9-22.3)
Subtype D
UVRI (Mpigi) 5.9 (3.1- 8.8) 8.0 (2.8-12.4) 6.9 (2.8-12.4)
Mulago (Kampala) 7.9 (3.6-12.4) 6.7 (3.1- 9.8%) 7.2 (3.1-12.4)
Nsambya (Kampala) 6.4 (3.3- 9.5) 8.5 (3.9-12.5) 7.4 (3.3-12.5)

a Since two isolates from 1994-1995 were almost identical and may represent persons who were epidemiologically linked, these were treated as one sequence for overall calculations.
bUVRI = Uganda Virus Research Institute.

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