Volume 6, Number 6—December 2000
Research
Predominance of HIV-1 Subtype A and D Infections in Uganda
Dale J. Hu*
, James Baggs†, Robert G. Downing*†, Danuta Pieniazek*, Jonathan Dorn*, Carol Fridlund*, Benon Biryahwaho‡, Sylvester D.K. Sempala‡, Mark A. Rayfield*, Timothy J. Dondero*, and Renu Lal*
, James Baggs†, Robert G. Downing*†, Danuta Pieniazek*, Jonathan Dorn*, Carol Fridlund*, Benon Biryahwaho‡, Sylvester D.K. Sempala‡, Mark A. Rayfield*, Timothy J. Dondero*, and Renu Lal*Table 2
Mean (and range) percentage of pairwise nucleotide divergence stratified by time period, subtype, and clinic (district)
| % Mean (range) |
|||
|---|---|---|---|
| Subtype by clinic (district) | 1994/95 | 1997 | Overall |
| Subtype Aa | |||
| UVRIb (Mpigi) | 5.0 (3.6- 9.5) | 7.7 (3.9-12.6) | 6.4 (3.6-12.6) |
| Mulago (Kampala) | 7.3 (3.9-10.4) | 8.3 (4.2-14.0) | 7.8 (3.9-14.0) |
| Nsambya (Kampala) | 7.3 (3.9-11.7) | 10.8(3.9-22.3) | 9.1 (3.9-22.3) |
| Subtype D | |||
| UVRI (Mpigi) | 5.9 (3.1- 8.8) | 8.0 (2.8-12.4) | 6.9 (2.8-12.4) |
| Mulago (Kampala) | 7.9 (3.6-12.4) | 6.7 (3.1- 9.8%) | 7.2 (3.1-12.4) |
| Nsambya (Kampala) | 6.4 (3.3- 9.5) | 8.5 (3.9-12.5) | 7.4 (3.3-12.5) |
a Since two isolates from 1994-1995 were almost identical and may represent persons who were epidemiologically linked, these were treated as one sequence for overall calculations.
bUVRI = Uganda Virus Research Institute.
