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Volume 6, Number 6—December 2000

Research

Risk Factors for Otitis Media and Carriage of Multiple Strains of Haemophilus influenzae and Streptococcus pneumoniae

Jennifer St. Sauver*, Carl F. Marrs*, Betsy Foxman*, Patricia Somsel†, Robbie Madera*, and Janet R. Gilsdorf*Comments to Author 
Author affiliations: *University of Michigan, Ann Arbor, Michigan, USA; †Regional Medical Laboratories Inc, Battle Creek, Michigan, USA

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Table 4

Multivariate logistic regression odds ratios and 95% confidence intervalsa predicting carriage of two or more genetically distinct Haemophilus influenzae isolates during a sampling period.

Risk Factor Carriage of two or more H. influenzae genetic types (N=54) OR (95% CI)
Exposed to smoking 3.89 (1.83-8.28)
Allergies 2.48 (1.03-5.95)
Age
24-35 months 0.60b (0.28-1.27)
36-47 months 3.43b (1.35-8.71)
48+ months 1.28b (0.49-3.32)
Antibiotic use 0.26 (0.07-1.01)

a Logistic regression performed with the generalized estimating equations (GEE) SAS macro to control for correlation between multiple samples taken from the same children. All risk factors were included in a single model.
b Odds ratios compared with 23-month age group.

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