TY - JOUR AU - Chowdhury, Nandini Roy AU - Chakraborty, Soumen AU - Ramamurthy, Thandavarayan AU - Nishibuchi, Mitsuaki AU - Yamasaki, Shinji AU - Takeda, Yoshifumi AU - Nair, Gopinath Balakrish T1 - Molecular Evidence of Clonal Vibrio parahaemolyticus Pandemic Strains T2 - Emerging Infectious Disease journal PY - 2000 VL - 6 IS - 6 SP - 631 SN - 1080-6059 AB - The upsurge in worldwide incidence of Vibrio parahaemolyticus infection in the last 5 years has been attributed to the recent appearance of three serotypes with pandemic potential: O3:K6, O4:K68, and O1:K untypeable (KUT). Thirty-five strains of these serotypes, isolated from different countries over 4 years, were characterized by ribotyping and pulsed-field gel electrophoresis to determine their origin. The ribotypes of the strains of these serotypes were indistinguishable, except for a Japanese tdh- negative O3:K6 strain and a U.S. clinical O3:K6 isolate, which had slightly different profiles. The migration patterns of the NotI-digest of the total DNA of the strains were similar, and only slight variations were observed between the serotypes. By contrast, the O3:K6 and O1:KUT strains isolated before 1995 and strains of other serotypes had markedly different profiles. The O4:K68 and O1:KUT strains most likely originated from the pandemic O3:K6 clone. KW - vibrio parahaemolyticus KW - O3:K6 KW - O4:K68 KW - O1:K untypeable (KUT) KW - ribotyping KW - India KW - Japan DO - 10.3201/eid0606.000612 UR - https://wwwnc.cdc.gov/eid/article/6/6/00-0612_article ER - End of Reference