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Volume 7, Number 1—February 2001

Perspective

Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease: Background, Evolution, and Current Concerns

Paul Brown*Comments to Author , Robert G. Will†, Raymond Bradley‡, David M. Asher§, and Linda Detwiler¶
Author affiliations: *National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA; †National Creutzfeldt-Jakob Disease Surveillance Unit, Western General Hospital, Edinburgh, Scotland; ‡Central Veterinary Laboratory, New Haw, Addlestone, UK; §Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, Maryland, USA; ¶Animal and Plant Health Inspection Service, U.S. Department of Agriculture, Robbinsville, New Jersey, USA

Main Article

Table 3

Chronology of variant Creutzfeld-Jakob disease (vCJD) in the United Kingdom and other European countries, as of December 2000

Year of onset United Kingdom France Ireland
1994 8 1
1995 10
1996 11
1997 14
1998 17
1999a 20 (+4) 1 (+1) 1
2000a 1 (+2)

aParentheses indicate still-living persons with probable vCJD or deceased persons whose diagnoses have not yet been confirmed by neuropathologic examination. In 2000, additional cases have been identified that do not yet meet the minimum clinical criteria for a premortem diagnosis of "probable" vCJD. Dates are for year of onset of illness, not year of death.

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