Volume 7, Number 3—June 2001
Is High Prevalence of Echinococcus multilocularis in Wild and Domestic Animals Associated with Disease Incidence in Humans?
|Blood donors tested (total)||2,943|
|Em2-positive blood donorsb||6b||(0.2)||[0.04-0.36]|
|EgHF-positive blood donors but negative by Em2||33c||(1.1)||[0.5-2.1]|
aAssessed primarily by Em2-enzyme-linked immunosorbent assay (ELISA), complementary serologic data were obtained with the E. granulosus hydatid fluid antigen-ELISA. Blood samples were collected from October 1996 to July 1997.
bFour of six Em2-positive blood donors received imaging investigations, one of which was computed tomography-positive for an alveolar hydatid disease (AHD) lesion. Two Em2-positive donors refused subsequent imaging investigations but have had no signs of AHD.
cTen donors with high E. granulosus hydatid fluid antigen-titers but negative in Em2-ELISA were selected for pilot imaging investigations. One had a cystic hepatic lesion of 2.5 cm in diameter. Morphologic features were compatible with those of E. granulosus cysts.