Volume 7, Number 3—June 2001
Research
Molecular Epidemiology of Serogroup A Meningitis in Moscow, 1969 to 1997
, Arie van der Ende†, Peixuan Zhu*, Irina S. Koroleva‡, Barica Kusecek*, Giovanna Morelli*, Ilse G.A. Schuurman†, Norbert Brieske*, Kerstin Zurth*, Natalya N. Kostyukova§, and Alexander E. Platonov‡Table 4
Hypervariable alleles among subgroup III meningococci isolated in Moscow
| Locus |
|||||||||
|---|---|---|---|---|---|---|---|---|---|
| Strains | No. | tbpB | iga | pgm | IS1106 | opaA | opaB | opaD | opaJ |
| agenocloud 1 | 1 | 2 | 3 | A10 | 132 | 92 | 131 | 101 | |
| genocloud 3 | 1 | 2 | 3 | A4 | 132 | 92 | 131 | 101 | |
| genocloud 5 | 1 | 3 | 3 | A4 | 132 | 94 | 100 | 101 | |
| genocloud 8 | 55 | 2 | 19 | A7 | 132 | 92 | 131 | 101 | |
| Moscow genocloud 2 | |||||||||
| 1969-1973 | 14 | 38 | 2 | 3 | A10 | 132 | 140 | 131 | 101 |
| 1970 | 1 | 38 | 2 | 3 | A10 | 132 | 113 | 131 | 101 |
| 1977 | 1 | 38 | 2 | 3 | A10 | 132 | 140 | 110 | 101 |
| 1977 | 1 | 38 | 2 | 3 | ndb | 132 | 140 | 109 | 101 |
| Moscow genocloud 8 | |||||||||
| 1994-1997 | 21 | 55 | 2 | 19 | A7 | 132 | 92 | 131 | 101 |
aData for the genoclouds at the top of the table are from a separate manuscript (23). Sources of genoclouds: 1, China, 1966; 3, pre-Mecca isolates (1969-1984) from Europe, Brazil and China; 5, post-Mecca isolates (1987-1998) from Africa and pilgrims returning from Mecca in 1987 to various countries; and 8, China, Mongolia, and Africa, 1993-2000. All serogroup A isolates from Moscow that were assigned to subgroup III by random amplification of polymorphic DNA are included in this table. The opaA and opaJ alleles have not been tested in all bacteria from the various genoclouds because they are otherwise so uniform.
bnd = not determined because this strain yields an unusual 12-kb polymerase chain reaction product for the IS1106A region.
