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Volume 7, Number 3—June 2001

Dispatch

Decreased Susceptibility to Ciprofloxacin in Salmonella enterica serotype Typhi, United Kingdom

E. John ThrelfallComments to Author  and Linda R. Ward
Author affiliations: Central Public Health Laboratory, London, United Kingdom

Main Article

Table 1

Incidence of multidrug resistance and decreased susceptibility to ciprofloxacin in Salmonella enterica serotype Typhi, U.K., 1990-1999

CPL strains also resistant to:
Year Strainsa MDRB no. (%) Decreased susceptibility to CPL no (/%) C A Tm Ct Cf
1990 248 50 (20) 0 (0) 0 0 0 0 0
1991 226 48 (21) 2 (0.9) 1 1 1 0 0
1992 204 49 (24) 1 (0.5) 0 0 0 0 0
1993 194 49 (25) 1 (0.5) 1 1 1 0 0
1994 259 94 (36) 5 (2) 5 5 5 0 0
1995 291 100 (34) 8 (3) 5 5 5 0 0
1996 210 52 (25) 11 (7) 7 7 7 0 0
1997 174 22 (13) 9 (5) 6 6 6 0 0
1998 151 34 (23) 32 (21) 19 19 19 0 0
1999 179 47 (26) 42 (23) 25 25 25 0 0

aStrains referred to Laboratory of Enteric Pathogens.
bMDR = multidrug resistant (to chloramphenicol, ampicillin, and trimethoprim). Resistance symbols: C, chloramphenicol; A, ampicillin; Tm, trimethoprim; CPL, ciprofloxacin (MIC 0.25-1.0 mg/L); Ct, ceftriaxone; Cf, cefotaxime. Percentages of total isolates in parentheses.

Main Article

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