Volume 7, Number 3—June 2001
Dispatch
VEB-1-like Extended-Spectrum ß-Lactamases in Pseudomonas aeruginosa, Kuwait
Laurent Poirel*, Vincent O. Rotimi†, Eiman M. Mokaddas†, Amal Karim*, and Patrice Nordmann*
Table
MICs of beta-lactams for Pseudomonas aeruginosa KU-1 and KU-2 clinical isolates, P. aeruginosa PU21(pROT-1), and PU21 reference strain
| MICs (mg/L) |
||||
|---|---|---|---|---|
| Antibiotica | P. aeruginosa KU-1 | P. aeruginosa KU-2 | P. aeruginosa PU21 (pROT-1) | P. aeruginosa PU21 |
| Amoxicillin | >512 | >512 | >512 | 64 |
| Ticarcillin | >512 | 512 | 512 | 16 |
| Ticarcillin+CLA | 64 | 16 | 16 | 16 |
| Piperacillin | 64 | 16 | 16 | 2 |
| Piperacillin+TZB | 32 | 8 | 8 | 1 |
| Ceftazidime | 512 | 512 | 512 | 0.25 |
| Ceftazidime+CLA | 16 | 8 | 8 | 0.25 |
| Ceftazidime +TZB | 8 | 4 | 8 | 0.50 |
| Cefotaxime | 512 | 128 | 128 | 4 |
| Cefotaxime+CLA | 64 | 16 | 16 | 2 |
| Impenem | 2 | 2 | 2 | 0.12 |
| Aztreonam | >512 | >512 | 512 | 0.5 |
| Aztreonam+CLA | 64 | 8 | 8 | 0.5 |
aCLA: clavulanic acid at a fixed concentration of 2 mg/L; TZB: tazobactam at a fixed concentration of 4 mg/L.
