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Volume 7, Number 3—June 2001

Dispatch

VEB-1-like Extended-Spectrum ß-Lactamases in Pseudomonas aeruginosa, Kuwait

Laurent Poirel*, Vincent O. Rotimi†, Eiman M. Mokaddas†, Amal Karim*, and Patrice Nordmann*Comments to Author 
Author affiliations: *Faculté de Médecine Paris-Sud, Le Kremlin-Bicêtre, France; †Kuwait University, Kuwait

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Table

MICs of beta-lactams for Pseudomonas aeruginosa KU-1 and KU-2 clinical isolates, P. aeruginosa PU21(pROT-1), and PU21 reference strain

MICs (mg/L)
Antibiotica P. aeruginosa KU-1 P. aeruginosa KU-2 P. aeruginosa PU21 (pROT-1) P. aeruginosa PU21
Amoxicillin >512 >512 >512 64
Ticarcillin >512 512 512 16
Ticarcillin+CLA 64 16 16 16
Piperacillin 64 16 16 2
Piperacillin+TZB 32 8 8 1
Ceftazidime 512 512 512 0.25
Ceftazidime+CLA 16 8 8 0.25
Ceftazidime +TZB 8 4 8 0.50
Cefotaxime 512 128 128 4
Cefotaxime+CLA 64 16 16 2
Impenem 2 2 2 0.12
Aztreonam >512 >512 512 0.5
Aztreonam+CLA 64 8 8 0.5

aCLA: clavulanic acid at a fixed concentration of 2 mg/L; TZB: tazobactam at a fixed concentration of 4 mg/L.

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